Bio-Molecular Networks

Coordinators: Deborah Kuchnir Fygenson, Andrei Ruckenstein, Boris Shraiman, L. Wolpert

The program will address the "information, regulation and control" issues in intracellular processes by focusing specifically on:
  1. Enzymatic signal transduction pathways(which underlie coordinated response of the cell to external and internal stimuli)
  2. Genetic networks(which employ transcription factor proteins to control the timely expression of genes required for normal cell function or cell differentiation during development).
The goals of the proposed program are:
  1. to explore the avenues of quantitative modeling, experimentation and analysis within the above areas and to forge quantitative tools of discovery;
  2. to foster interactions between the biology and physics communities, and experimental and theoretical/computational approaches
  3. to seek insight into the general "design principles" which govern the organization of regulatory networks and are responsible for the apparent "robustness"(i.e. stability with respect to mutation) and "evolvability"(i.e. ability to acquire new function) of living matter, thus underlying the diversity of life forms.

For more news: Program Information
Participant Information:Participants
Shortcourse: Robustness Analysis Tools with Applications to the Biological and Physical Sciences.