Timescales of Plasticity and Underlying Mechanisms
Coordinators: József Fiser, Máté Lengyel, and Jennifer Raymond
A long-standing question in the neurobiology of learning is that of timescales. The brain can associate events that are separated by seconds, minutes, hours, days, weeks, or longer. Yet, the known biological mechanisms for inducing changes in the synaptic connections between neurons are driven by neural events that are separated by typically no more than a few tens or hundreds of milliseconds. This conference will convene scientists studying the molecular, cellular, and circuit-level mechanisms used by the brain to bridge the multiple timescales across which events play out in the experience of an individual. The goal will be to assemble an up-to-date understanding of the set of biological mechanisms available in the brain to support associative learning across different timescales. The conference's emphasis on biological mechanisms will complement and support the main program’s more computational focus, and encourage an integrated analysis of statistical learning spanning molecular, cellular, circuit, and behavioral-level phenomena.
PLEASE NOTE: During the conference there will be an opportunity to present a poster. If you are interested in presenting a poster please visit the conference website and submit your title and abstract. Each poster board is 4 feet high x 6 feet wide. We ask that the posters be no larger than 44 inches high x 34 inches wide at the most (it is important to follow these measurements or posters may be turned down due to limited space). The deadline to submit a poster is July 5.
Invited Speakers:
Cliff Abraham - Univ. of Otago
Allison Barth - CMU
Dean Buonomano - UCLA
Christine Grienberger - Brandeis
Leslie Griffith - Brandeis
Yasunori Hayashi - Kyoto Univ.
Rich Kramer - UC Berkeley
Janine Kwapis - Penn State
Máté Lengyel - Cambridge
Mathieu Letellier - Univ. of Bordeaux
Steve Lisberger - Duke
Tom O'dell - UCLA
Azahara Oliva - Cornell
Jennifer Raymond - Stanford
Megha Sehgal - UCLA
Laurent Venance - INSERM
TELEFAX: (805) 893-2431
speakers@kitp.ucsb.edu
SANTA BARBARA, CA 93106-4030
http://www.kitp.ucsb.edu
Coordinators: József Fiser, Máté Lengyel, and Jennifer Raymond
Day of Jul 10, 2023
2023
Monday, Jul 10, 2023
-
08:50AM Behaviorally relevant synaptic plasticity rules
Fred Kavli Auditorium (Main)
Talks are 30 min + 15 min discussion
- 08:50AM Lars Bildsten (KITP) Welcome
- 09:00AM Laurent Venance (INSERM) Striatum expresses region-specific plasticity consistent with distinct memory abilities
- 09:45AM Christine Grienberger (Brandeis Univ.) Behavioral timescale plasticity in the hippocampus
-
10:30AM MORNING BREAK
Gurley Courtyard
-
11:00AM
Fred Kavli Auditorium (Main)
- 11:00AM Jennifer Raymond (Stanford) Adaptive tuning of the timing rules for plasticity to circuit properties
- 11:45AM Perspectives & Discussion: Behaviorally relevant synaptic plasticity rules
-
12:30PM LUNCH BREAK
Gurley Courtyard
-
02:00PM Synaptic cooperativity/independence
Fred Kavli Auditorium (Main)
Talks are 30 min + 15 min discussion
- 02:00PM Thomas O'Dell (UCLA) Behavioral Timescale Cooperativity and Competitive Synaptic Interactions
- 02:45PM Alison Barth (CMU) Transient and layer-specific reduction in neocortical PV inhibition during sensory association learning
-
03:30PM AFTERNOON BREAK
Gurley Courtyard
-
04:00PM
Fred Kavli Auditorium (Main)
- 04:00PM Mathieu Letellier (Univ. of Bordeaux) miR-124-dependent tagging of synapses by synaptopodin enables input-specific homeostatic plasticity
- 04:45PM Perspectives & Discussion: Synaptic cooperativity/independence
-
05:30PM RECEPTION
Gurley Courtyard
-
06:00PM SPECIAL EVENTS DINNER
Gurley Courtyard
-
08:00PM SHUTTLE TO BWSCI
Gurley Courtyard
TELEFAX: (805) 893-2431
speakers@kitp.ucsb.edu
SANTA BARBARA, CA 93106-4030
http://www.kitp.ucsb.edu
Coordinators: József Fiser, Máté Lengyel, and Jennifer Raymond
Week of Jul 10 - Jul 16, 2023
2023
Monday, Jul 10, 2023
-
08:50AM Behaviorally relevant synaptic plasticity rules
Fred Kavli Auditorium (Main)
Talks are 30 min + 15 min discussion
- 08:50AM Lars Bildsten (KITP) Welcome
- 09:00AM Laurent Venance (INSERM) Striatum expresses region-specific plasticity consistent with distinct memory abilities
- 09:45AM Christine Grienberger (Brandeis Univ.) Behavioral timescale plasticity in the hippocampus
-
10:30AM MORNING BREAK
Gurley Courtyard
-
11:00AM
Fred Kavli Auditorium (Main)
- 11:00AM Jennifer Raymond (Stanford) Adaptive tuning of the timing rules for plasticity to circuit properties
- 11:45AM Perspectives & Discussion: Behaviorally relevant synaptic plasticity rules
-
12:30PM LUNCH BREAK
Gurley Courtyard
-
02:00PM Synaptic cooperativity/independence
Fred Kavli Auditorium (Main)
Talks are 30 min + 15 min discussion
- 02:00PM Thomas O'Dell (UCLA) Behavioral Timescale Cooperativity and Competitive Synaptic Interactions
- 02:45PM Alison Barth (CMU) Transient and layer-specific reduction in neocortical PV inhibition during sensory association learning
-
03:30PM AFTERNOON BREAK
Gurley Courtyard
-
04:00PM
Fred Kavli Auditorium (Main)
- 04:00PM Mathieu Letellier (Univ. of Bordeaux) miR-124-dependent tagging of synapses by synaptopodin enables input-specific homeostatic plasticity
- 04:45PM Perspectives & Discussion: Synaptic cooperativity/independence
-
05:30PM RECEPTION
Gurley Courtyard
-
06:00PM SPECIAL EVENTS DINNER
Gurley Courtyard
-
08:00PM SHUTTLE TO BWSCI
Gurley Courtyard
2023
Tuesday, Jul 11, 2023
-
09:00AM Metaplasticity
Fred Kavli Auditorium (Main)
Talks are 30 min + 15 min discussion
- 09:00AM Rich Kramer (UC Berkeley) Relocation of an Extrasynaptic GABAA Receptor to Inhibitory Synapses Freezes Excitatory Synaptic Strength and Preserves Memory
- 09:45AM Cliff Abraham (Univ. of Otago) Pathway-specific TNF-mediated metaplasticity in hippocampal area CA1e
-
10:30AM MORNING BREAK
Gurley Courtyard
-
11:00AM
Fred Kavli Auditorium (Main)
- 11:00AM Dean Buonomano (UCLA) Meta- short-term plasticity for temporal coding
- 11:45AM Perspectives & Discussion: Metaplasticity
-
12:30PM LUNCH BREAK
Gurley Courtyard
-
02:00PM SHUTTLE TO BWSCI
Gurley Courtyard
FREE AFTERNOON
2023
Wednesday, Jul 12, 2023
-
09:00AM Systems Consolidation
Fred Kavli Auditorium (Main)
Talks are 30 min + 15 min discussion
- 09:00AM Leslie Griffith (Brandeis Univ.) Role of sleep in memory consolidation
- 09:45AM Steve Lisberger (Duke) Principles of operation of a cerebellar learning circuit
-
10:30AM MORNING BREAK
Gurley Courtyard
-
11:00AM
Fred Kavli Auditorium (Main)
- 11:00AM Yasunori Hayashi (Kyoto Univ.) Stepwise synaptic plasticity events drive the early phase of memory consolidation
- 11:45AM Azahara Oliva (Cornell) Long-duration Hippocampal Sharp Wave Ripples Improve Memory
-
12:30PM LUNCH BREAK
Gurley Courtyard
-
02:00PM Discussion & Poster Session
Fred Kavli Auditorium (Main)
Talks are 30 min + 15 min discussion
- 02:00PM Perspectives & Discussion: Systems consolidation
- 02:45PM Poster session
-
03:30PM AFTERNOON BREAK
Gurley Courtyard
-
04:00PM Discussion & Poster Session
Fred Kavli Auditorium (Main)
- 04:00PM Poster session
-
05:30PM RECEPTION
Gurley Courtyard
-
06:00PM SPECIAL EVENTS DINNER
Gurley Courtyard
-
08:00PM SHUTTLE TO BWSCI
Gurley Courtyard
2023
Thursday, Jul 13, 2023
-
09:00AM Memory updating
Fred Kavli Auditorium (Main)
Talks are 30 min + 15 min discussion
- 09:00AM Megha Seghal (UCLA) Memory linking
- 09:45AM Máté Lengyel (Cambridge) Contextual inference underlies the learning of sensorimotor repertoires
-
10:30AM MORNING BREAK
Gurley Courtyard
-
11:00AM
Fred Kavli Auditorium (Main)
- 11:00AM Janine Kwapis (Penn State) Molecular Mechanisms of Reconsolidation-Dependent Memory Updating
- 11:45AM Perspectives and Discussion: Memory updating
-
12:30PM LUNCH
Gurley Courtyard
-
02:00PM CONFERENCE END SHUTTLE TO BWSCI *Also available to SB Airport and SB Airbus, Goleta location (See Registration Desk BEFORE THURSDAY to sign up.)
Gurley Courtyard
2023
Friday, Jul 14, 2023
No talks scheduled.
2023
Saturday, Jul 15, 2023
No talks scheduled.
2023
Sunday, Jul 16, 2023
No talks scheduled.