Nervous systems efficiently collect sensory information from the environment and adapt their behavior accordingly. This process predominantly involves active movement of the body and sensory appendages to sample space through purposeful actions and more elaborate strategies to explore complex sensory landscapes. For example, dogs and mice investigate their olfactory world through intermittent sniffs and head movements. Ants and flies move their bodies, eyes, and antenna to collect information while navigating changing environments. An animal’s intentional movements can enhance–or confound–its ability to collect sensory information. Thus sensation, perception, and motor actions are components of a unified, feedback process of "active sensation.” Parsing self-generated from externally-derived sensory cues is essential to organizing appropriate sensory-motor responses. This program will bring together experimentalists and theorists to work across model systems for productive collaborations that tackle these outstanding questions.