Contrary to what Watson and Crick enunciated in their "central dogma" soon after they figured out the genetic code, biologists in recent years have elucidated the central role played by RNA. Indeed, current speculations on the origin of life generally place RNA before DNA. Biological functions depend largely on the shape of the molecules involved and thus understanding how RNA folds into the correct shape has emerged as an important problem in biology. Clearly, shape and topology (the branch of mathematics concerned with the difference between a ball and a doughnut) are relevant here. Given this fascinating interplay between mathematics and physics, the subject encourages an inter-disciplinary approach, requiring the efforts of theoretical physicists, mathematicians, as well as that of biochemists. I will describe an approach using quantum field theories with its built in topological character. This talk will not presuppose any knowledge of quantum field theory and mathematics. Instead I will use color (literally) to explain certain topological properties of Feynman diagrams.
